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Pentobarbital is surely an injection meant for use in medical options by Health care industry experts. Diversion and misuse are illegal.pentobarbital will minimize the level or impact of fentanyl transmucosal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Closely. Coadministration of fentanyl with CYP3A4 inducers c